Tingling sensation is natural. You may experience a tingling sensation, which may last for some time, but rest assured that this is a natural reaction to the Zero Exosome Shot.

Drawing upon the principles of microneedling, we've crafted a micro-sized, needle-shaped booster to target a range of skin issues. Enhanced with 15M patented Exosome shots, this formula physically delivers active ingredients to pores, providing daily intensive treatments for home use. Clinically validated to care for pore size, smooth skin texture, strengthen the skin barrier, and promote a radiant complexion.

• Non-comedogenic
• Tested to be Low-Irritating
• Gluten-Free
• No artificial color

• Results from a consumer use study 100% Feels like receiving professional care, providing a pleasant sensation.
  Overall product satisfaction.
  Positive feedback from a 20-person survey, with individual variances.
  Tested by the Global Institute of Dermatological Science.
  Test period: August 24, 2022 - September 21, 2022.
• Results from a self test report Absorption of active ingredients
  Absorption of active ingredients in cosmetics compared to standalone use +242%
  Pore Care Effect
  Pore density care -21.1%
  Decrease in pore visibility -21.1%
  Pore area -15.3%
  Pore volume -16.7%
  Other skin enhancements
  Dead Skin Cells improvement +88.7%
  Enhancement of radiance +51.7%
  Sebum improvement +8.9%
  Surface hydration enhancement +7.6%
  Texture refinement +4.1%
  Skin barrier enhancement +54.2%
  Line volume care +10.4%
  Melanin pigmentation improvement +7.4%
  Freckles, blemishes visibility care +4.8%
  * Excerpt from Therapium Exosome Shot Test Report and Survey, Results may vary.

• Exosome-coated Spicule (Hydrolyzed sponge)Taking the form of needles, spicules penetrate the epidermal layer of the skin, providing next generation care for pores and overall healthier skin. While various skincare products feature Spicules, none are quite like Exosome Shot, which contains Exosome-coated Spicules.
• Lacto Exosome A patented active ingredient in Medicube, effectively cares for damaged skin, providing vitality and energy Comprised of various active ingredients including peptides, amino acids, glutathione, and vitamins, Medicube's patented Exosome addresses daily skin concerns and promotes natural skin health.
• AHA + BHA + PHAPowerhouse ingredients that aid in resurfacing textured skin, dissolving dead skin cells, and promoting skin renewal.
• NiacinamideBoosts the skin’s barrier and delivers hydration.
• PanthenolSoothes the skin and helps improve hydration levels.
• *All the descriptions above are limited to raw material characteristics.

• Formulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols, nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum Salts and complexes in antiperspirants, Animal Musk's/Fats/Oils, Benzophenones and related compounds, Benzyl Alcohol, Black 3, Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone, Latex, Lead and Lead Acetate, Mercury and Mercury Compounds (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve (Ethylene glycol monomethyl ether or 2-Methoxyethanol), Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT), Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate, Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS), Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine, phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS compounds, Plastic Microbeads, Polyacrylamide and Acrylamide, Polyethylene microbeads, polypropylene microbeads & polystyrene microbeads (restricted in rinse-off products only), Resorcinol, Retinol and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal, Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and more.

• Q. Is it normal for my face to tingle after application?Exosome Shot Ampoule contains naturally derived micro-particle ingredients, which may cause a tingling sensation upon application.
  This is a natural reaction as the active ingredients are being delivered to the pores.
  We recommend adjusting the amount and frequency of use based on individual skin sensitivity.
• Q. Do I simply wash it off or do I maintain my regular skincare routine afterwards?This product is not meant to be rinsed off.
  Instead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.
• Q. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?Exosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).
  The Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.
• Q. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?The spicules are designed to naturally shed along with the dead skin over several days after application.
  Any residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.
• Q. Are there any ingredients that should not be used together with it?There are no specific ingredients that should not be used together; however, individuals with sensitivity should be cautious as certain ingredients may cause irritation or hypersensitivity reactions.
  Please conduct a patch test and adjust the amount and frequency of use accordingly.
• Q. I want to focus on managing my pores. Are there any synergistic products that work well together?When used in conjunction with the Exosome Shot, the One-day Serum and One-day Cream result in an 88% improvement in pore volume and an 85% improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot Ampoule first, followed by the One-day Serum, and finishing with the One-day Cream.
  * Excerpts from in vivo absorption tests for improving skin absorption depth compared to using One-day Serum + One-day Cream alone. / Individual results may vary.